Use the Exchange admin center to enable or disable email apps
- In the EAC, navigate to Recipients > Mailboxes.
- In the list of user mailboxes, select the mailbox that you want to enable or disable email apps for. A display pane is shown for the selected user mailbox.
- On the General tab, under Email apps & mobile devices, select the Manage email apps settings link.
- In the Manage settings for email apps display pane, set Outlook desktop (MAPI), Mobile (Exchange ActiveSync), IMAP, POP3 and Outlook on the web to Enabled or Disabled
- Select Save to save your change. A message Email app settings updated successfully is displayed. Select Close to exit.
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Bonus (Power User Tip):
For advanced configuration using PowerShell, check out this Microsoft guide.